WebDec 4, 2010 · Fig. 1. The substrates of MYST acetyltransferases can be classified in distinct classes. The majority of the MYST acetyltransferases substrates are nuclear, although cytoplasmic substrates have been reported recently. The best studied MYST substrate class is histones, namely histones H4, H3, H2A and H2A variants. WebJun 23, 2024 · The carrier cycles between two states, which are conventionally called the matrix-open state and the cytoplasmic-open state, because of the orientation of the substrate-binding site towards these ...
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WebJul 29, 2008 · In the resulting model (Fig. 5B), the extracellular end of the bundle is closer to TM3 and -10, and the cytoplasmic end of the bundle is further from TMs 5 and 8, breaking the Arg-5/Asp-369 ion pair at the cytoplasmic surface and effectively opening an aqueous pathway from the cytoplasm to the substrate binding site. The primary difference ... WebNational Center for Biotechnology Information madout2 download pc windows 11
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