Ef hand family
WebHow to Link to the Data Library. The EF-Hand Calcium-Binding Proteins Data Library is a growing collection of published sequence, structural, functional, and other … WebEF-hand motif referred to as the pseudo EF-hand is found in members of the S100 protein family. More recently, structures of EF-hand proteins containing an 11-residue Ca2C-binding loop (calpain,40,41 grancalcin,42 ALG-243)or a 13-residue loop (SPARC/osteonectin/BM-4044) became available and provided evidence that similar …
Ef hand family
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The EF hand is a helix–loop–helix structural domain or motif found in a large family of calcium-binding proteins. The EF-hand motif contains a helix–loop–helix topology, much like the spread thumb and forefinger of the human hand, in which the Ca ions are coordinated by ligands within the loop. The motif … See more The calcium ion is coordinated in a pentagonal bipyramidal configuration. The six residues involved in the binding are in positions 1, 3, 5, 7, 9 and 12; these residues are denoted by X, Y, Z, -Y, -X and -Z. The … See more Pattern (motif signature) search is one of the most straightforward ways to predict continuous EF-hand Ca -binding sites in proteins. Based on the sequence alignment results of … See more Aequorin Aequorin is a calcium binding protein (CaBP) isolated from the cnidarian Aequorea victoria. Aequorin belongs to the EF-hand family of … See more • Branden C, Tooze J (1999). "Chapter 2: Motifs of protein structure". Introduction to Protein Structure. New York: Garland Pub. pp. 24–25. ISBN 0-8153-2305-0. • Nakayama S, Kretsinger RH (1994). "Evolution of the EF-hand family of proteins". Annu … See more Since the delineation of the EF-hand motif in 1973, the family of EF-hand proteins has expanded to include at least 66 subfamilies thus far. EF-hand motifs are divided into two … See more • Another distinct calcium-binding motif composed of alpha helices is the dockerin domain. See more • Eukaryotic Linear Motif resource motif class LIG_EH_1 • Eukaryotic Linear Motif resource motif class LIG_IQ See more WebJan 5, 2024 · SOS3 Calcium-binding EF-hand family protein [ (thale cress)] Gene ID: 832494, updated on 28-Aug-2024 Summary encodes a calcium sensor that is essential for K+ nutrition, K+/Na+ selectivity, and salt tolerance.
WebJan 1, 1989 · Abstract. The EF-hand homolog proteins bind calcium (Ca 2+) with dissociation constants in the micromolar range and are modulated by stimulus-induced increases in cytosolic free Ca 2+. We have grouped over 160 different EF-hand homolog proteins into ten subfamilies and ten unique categories. Except for troponin-C, all … WebDec 31, 2008 · Sorcin (so luble r esistance-related c alcium-binding protein) is a 22 kDa member of the penta-EF-hand family (PEF) of calcium-binding proteins (Maki et al. 1997).The best-characterized function of sorcin is its association with the cardiac ryanodine receptor (RyR; Meyers et al. 1995a).In response to the small calcium release triggered …
WebAug 5, 2024 · Strontium salts are used for treatment of osteoporosis and bone cancer, but their impact on calcium-mediated physiological processes remains obscure. To explore Sr2+ interference with Ca2+ binding to proteins of the EF-hand family, we studied Sr2+/Ca2+ interaction with a canonical EF-hand protein, α-parvalbumin (α-PA). Evaluation of the … WebCa2+-Binding Proteins of the EF-Hand Superfamily: Diagnostic and Prognostic Biomarkers and Novel Therapeutic Targets A multitude of Ca2+-sensor proteins containing the specific Ca2+-binding motif (helix-loop-helix, called EF-hand) are of major clinical relevance in a many human diseases.
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WebThe C2 domain is formed by eight β-strands which can bind two or three Ca 2+ -ions in the loop regions. In contrast, members of the EF-hand superfamily bind Ca 2+ through a well-characterized helix-loop-helix motif. With 250 identified members in the human genome, the EF-hand superfamily is the largest family of eukaryotic Ca 2+ -binding proteins. moisture rehab sally hansenWebHowever, the identities and functions of CBL gene family members in maize are largely unknown. Here, we identified from the maize genome 12 CBL genes. All 12 CBLs have conserved EF-hand domains, and half harbor myristoylation motifs. moisture resistant beadboard lowe\\u0027sWebJan 5, 2024 · Arabidopsis thaliana (ecotype: Columbia) Lineage Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; … moisture resistant loft boardsWebOct 21, 2024 · Calcium-binding EF-hand family protein; FUNCTIONS IN: calcium ion binding; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 … moisture resistant in ceiling speakersWebAug 31, 2024 · ALG-2 is a penta-EF-hand Ca2+-binding protein and interacts with a variety of proteins in mammalian cells. In order to find new ALG-2-binding partners, we … moisture resistant paneling lowesWebDec 1, 2011 · Plants have evolved a superfamily of EF-hand proteins represented by about 250 proteins in rice and Arabidopsis thaliana, a well studied model-plant, compared to 132 and 83 EF-hand proteins in Drosophila melanogaster and human respectively [4]. moisture resistant chipboard flooring b\\u0026qmoisture resistant spray paint hobby lobby